Background: Postoperative pulmonary complications (PPCs) are among the leading causes of morbidity, mortality, and increased length of stay (LOS). Methods: In a prospective cohort study, all adult candidates for all types of open-heart surgeries were enrolled and followed from admission to discharge for PPCs. Results: The study population consisted of 918 consecutive adult patients, including 574 (62. 5%) males, at a mean age of 56. 20±, 13. 95 (mean ±,standard deviation) years who underwent open cardiac surgery. Among them, 537 patients (58. 5%) suffered PPCs, comprising pleural effusion in 293/916 (32. 0%), atelectasis in 222 (24. 2%), pneumonia in 68 (7. 4%), diaphragm paralysis in 67 (7. 3%), pulmonary edema and/or acute respiratory distress syndrome in 64/915 (7. 0%), pneumothorax (in the right or left hemithorax) in 28/916 (3. 1%), hemothorax in 7/915 (0. 8%), subcutaneous emphysema in 11/913 (1. 2%), and empyema in 2/918 (0. 2) The independent risk factors for PPCs were age (OR, 1. 010,95% CI, 1. 001 to 1. 020,P=0. 0326), female sex (OR, 1. 375,95% CI, 1. 044 to 1. 811,P=0. 0235), and renal dysfunction (OR, 1. 553,95% CI, 1. 001 to 2. 409,P=0. 0497). Twenty-three patients died within 30 days of cardiac surgery, accounting for a hospital mortality rate of 2. 5%. Conclusions: The cumulative incidence rate of PPCs was 58. 5% in our center, with a mortality rate of 3. 4%. The overall mortality rate among all the patients was 2. 5%. The independent risk factors associated with PPCs were age, female sex, and renal failure.